产品目录

分子量：Approximately 7.8kDa,a single,non-glycosylated polypeptide chain containing 68 amino acids.
储存条件：冷冻（-20℃）

概述

CCL22 is a protein that in mouse is encoded by the CCL22 gene,which locates on the Chr.8.It is highly expressed in macrophage,monocyte-derived dendritic cell and thymus,additionally,also detected in the tissues of thymus,lymph node and appendix.CCL22 can bind to CCR4,and is a chemoattractant for monocytes,monocyte-derived dendritic cells,and natural killer cells,but not for neutrophils,eosinophils,and resting T-lymphocytes.After secreted from monocyte-derived dendritic cells,the protein can be proteolytic cleaved into three forms:MDC(3-69),MDC(5-69),MDC(7-69).

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human activated lymphocytes is in a concentration range of 10-100ng/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,150 mM NaCl.
内毒素	Less than 1 EU/μg of rMuMDC/CCL22 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	GPYGANVEDS ICCQDYIRHP LPSRLVKEFF WTSKSCRKPG VVLITVKNRD ICADPRQVWV KKLLHKLS

相关搜索：重组小鼠MDC/CCL22，MDC/CCL22, Murine